He was unknowingly Kovid-19. They now have rare antibodies in their blood.

With his roommate in critical health from coronovirus last spring, it didn’t take long for John Hallis to believe that he would also contract a highly contagious, lethal disease. Hollis said he was concerned about what might happen if he wrote a letter to his teenage son Davis, saying “things fell fast,” in the case, Hollis said.

It was discovered that Hallis was unknowingly already Kovid-19 and could have inadvertently infected his roommate.

Horis, communications manager at George Mason University in Fairfax, Virginia, learned in July that he falls into a rare category of people whose blood helps scientists understand Kovid-19 and potentially treat people who fall ill. Can.

Kovid-19, it seems, can do him no harm, Drs. Said Lance Liotta, a George Mason University pathologist and bioengineer who is leading the school’s clinical trials on antibodies.

A former journalist, 54-year-old Hollis, learned that his blood is fortified with so-called super antibodies – antibodies that neutralize the virus, which opposes Kovid-19 even when diluted 10,000 times, Liotta said.

It is a medical phenomenon found in less than 5 percent of the population who have contracted coronavirus, a study indicates, making Hollis and his blood a valuable resource in identifying potential treatments for Kovid-19.

“Through John and others, we have been propelled into exciting new science,” Liotta said. “Learning about their antibodies gives us new ways to fight Kovid.”

In short, the use of Hollis’s antibodies – the Y-shaped proteins in the blood used by the immune system to try and fight bacteria and viruses – Leota and his team, as part of their tests, called “exponential viruses. Understand exponentially better way to kill “mass production of genitals. John’s” to protect the general population from the virus, is like the drug Regineron, which President Donald Trump took after announcing in early October that He had tested positive.

“If this sounds crazy to you, imagine how it feels to me,” said Hollis, a former sports journalist at The Atlantis Journal-Constitution.

More than 20 million people in the United States have contracted the deadly virus as vaccines slowly become available. But treatment is still necessary for the virus, which makes Hollis’ “super” antibodies significantly important.

His story began after he took his son Davis on a trip to Europe in early March. After a long time he did not return from London and Paris and just before he flew to the United States, Hollis experienced the congestion he associated with common sinus issues that come with him for that time of year.

The symptoms quickly passed, but his roommate, who did not want to be named, became devastatingly ill with Kovid-19 for a month. Fearing for her friend, Hallis stood near her door every morning and listened to the movement to make sure she was still alive. Hollis continuously wiped out the townhouse she shared and confined herself to her bedroom.

John Hallis.Ron Eyra / George Mason University

“He was scared to death,” said Kevin W. Tidings, a lawyer in Charlotte, North Carolina. “I called him every week for just two weeks, checking on him. I was worried for him. He thought he would get it. But to his credit, he kept quiet and stayed there, because he was out. Didn’t want to go. And give it to someone else. “

He was particularly concerned about his son. Hallis said he was “horrified” that Davis may have contracted the Kovid-19 on his trip. He was also afraid that he might die of the virus and miss seeing his son grow into a man.

“I was at a strange peace, whatever happened to me, but saddened by the prospect that maybe not seeing my son hit my son with those major life milestones, such as graduating from high school, college And marrying and becoming a father himself, “said Hollis. “April 8, I sat down and wrote a letter to my son, to him that if I wasn’t here. I wrote the first sentence, and I cried. I read it every month, and I immediately cry.” I’m just thankful that I don’t have to give it to him. “

But Hallis did not fall ill at all. In mid-July, he volunteered to participate in a coronavirus study on campus supported by the new George Mason University President Gregory Washington and enthusiastically led by Leota, former deputy director of the National Institutes of Health.

Shortly afterwards, Liotta calls Hollis one night to tell him that he has disturbed the “super” antibodies.

Hollis said he remembered realizing that “absolutely shock”

“Here I was scared for my roommate and afraid that I would contract Kovid,” he said. “Instead, I already had and chances are he gave it to her. She got a bad deal. I feel so bad for her. And I can’t get it? I’m impenetrable for it? My antibodies Can modern science help? ” This was a lot for the process. “

George Mason University is one of 13 NIH-sponsored bio-level 3 biomedical research laboratories that have facilities for handling living Kovid-19 samples. When Lily had the virus Leota and her team were able to point it out. Halis was relieved that her son did not contract her.

“He’s in excellent health,” Hallis said.

Since August, Hallis has given blood and saliva samples every two weeks for laboratory testing and experiments. Liotta said that Hollis’s antibody levels are not only constant, but they have also been shown to be effective in killing six different strains of coronovirus.

Liotta’s team found seven other people with “super” antibodies for clinical testing. Hollis differs from others in that his antibodies retain 90 percent of their strength even after nine months of coronovirus. Liatta stated that most of the similar antibodies are destroyed in 60 to 90 days.

In addition, Liotta said, Hollis’s “super” antibody will help with the next phase of clinical testing – it will be tested in people who have taken the vaccine to ensure that their antibodies are elevated through injection .

“It’s all very exciting,” he said. “And it’s all due to our patients like John.”

The other public health officer, Drs. He is also enthusiastic, like Pierre Vigilance, an assistant professor of health policy and management at George Washington University School of Public Health, founder and head of HealthUp Strategic Advisors.

The vigilante, who led local emergency response efforts for the H1N1 outbreak in the Washington, DC, area in 2009, said he understands Leota’s enthusiasm.

“Think of a key and a lock,” said the vigilante. “The virus is a key to our cells. The coronovirus key is the spike protein, which can pick a lock and enter our cells. It’s very effective at doing this. An antibody is like a chewing gum that surrounds the key. Hardens. The key wins. ‘Does not go into the lock. So it prevents the virus from entering cells.

He said, “Super ‘antibodies are more effective in preventing viruses from entering our cells.” “About 75 percent of coronavirus patients have binding antibodies that do not neutralize the virus. Less than 5 percent of coronavirus patients have ‘super’ antibodies, which make them super important to replicate and use clinically. Make. The fact that so few people. To make such antibodies means that it is important to learn how to harvest and replicate it. “

Hollis is stunned by the search, but he still wears a mask and practices social distance. The severity of his condition has also dominated him for months.

“It is an understatement to say that it has become difficult to fully digest the experience,” he said. “Dr. Liotta and her team are amazing. On one hand, I am eternally grateful and feel blessed to still be healthy beyond measure and somehow have this rare natural protection against a deadly virus that is now Killing over 3,000 Americans. Everyone is being adversely affected, but especially African Americans and others of color.

“But, on the other hand, you only need to watch TV or any newspaper to see the great link of deaths and misery around the world as a result of the virus. It asks me: ‘Why me? When so many Why were I spared when there were no people? ”

He said that he stayed from late July to late night to enhance his experience.

“The truth is that I couldn’t give any real answer, maybe God has a plan for me,” he said. “Or maybe I’m lucky as hell.

“Somehow, I know that I have preached to my son for a long time that we all share a responsibility to make the world a better place when we arrived. Never once in a million years have I been this Can’t imagine how I could be. Just help me do that. “

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